Brain & Behavior Laboratory
ADHD and Narcolepsy Comorbidity
Modestino, E.J., & Winchester, J. (2013). A retrospective survey of childhood ADHD symptomatology among Adult Narcoleptics. Journal of Attention Disorders, 17(7), 574–582. https://doi.org/10.1177/1087054713480033
Medicine Lecture Series, Sleep Disorders Center, Department of Neurology, Boston University School of Medicine, Boston Medical Center, Boston, MA Wednesday, January 15, 2014
Dr. Modestino's blogs about this
Modestino, E. J., Blum, K., Oscar-Berman, M., Gold, M. S., Duane, D. D., Sultan, S. G. S., & Auerbach, S. H. (2015). Reward deficiency syndrome: Attentional/arousal subtypes, limitations of current diagnostic nosology, and future research. Journal of Reward Deficiency Syndrome, 01(01). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545661/
This is our latest publication. It is a genetic study that accessed databases and employed 7,171,168 subjects. The results revealed a shared genetic relationship between ADHD and narcolepsy (Genes: FOXP2, RBFOX1, and GRIN2A). This study was groundbreaking not only because of its results, but also due to the technique used.
Just published in July 2025!
Modestino EJ, Sharafshah A, Lewandrowski KU, Carey E, Mohankumar K, Thanos PK, et al. (2025) GWAS meta-meta-analysis and related analyses revealed a shared genetic background between ADHD and narcolepsy. Academia Molecular Biology and Genomics, 2. https://doi.org/10.20935/AcadMolBioGen7751
Editorial:
Modestino, E. J., Sharafshah, A., Lewandrowski, K.-U., Baron, D., Thanos, P. K., Lewandrowski, A. P. L., Badgaiyan, R. D., Dennen, C. A., & Blum, K. (2025). Narcolepsy: Like a rolling stone, a disorder without a neurobiological home...in need of answers. World Journal of Pharmaceutical Science and Research, 4(1), 44–47. https://doi.org/https://doi.org/10.5281/zenodo.14783720